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肿瘤与免疫研究室
2026-03-26 08:28:28 浏览次数:

Wang X, Wang H, Lu Z, Liu X, Chai W, Wang W, Feng J, Yang S, Yang W, Cheng H, Chen C, Zhang S, Sun N, Liu Q, Li Q, Song W, Jin F, Zeng Q, Wang S, Su Y, Wang H, Ni X, Gui J. Spatial and Single-Cell Analyses Reveal Heterogeneity of DNAM-1 Receptor-Ligand Interactions That Instructs Intratumoral γδT-cell Activity. Cancer Res. 2025 Jan 15;85(2):277-298. doi: 10.1158/0008-5472.CAN-24-1509. PMID: 39514370; PMCID: PMC11733534. 同题参见

Liu H, Zhang J, Wang Z, Wang W, Han D, Chen X, Su Y, Zhang J, Daniels C, Saulnier O, Wang ZJ, Gu C, Liu F, Deng K, Wang D, Feng Z, Zhao Y, Jiang Y, Gao Y, Liu Z, Ma M, Li Y, Zhao Z, Yuan H, Sun Y, Shi Y, Yang T, Li W, Qi X, Duan Z, Zhang J, Zhang M, Yu C, Jin W, Yu X, Tian Y, Li S, Li C, Taylor MD, Li J, Liu YQ, Qiu X, Jiang T. High cellular plasticity state of medulloblastoma local recurrence and distant dissemination. Cell Rep Med. 2025 Jan 21;6(1):101914. doi: 10.1016/j.xcrm.2024.101914. Epub 2025 Jan 13. PMID: 39809264; PMCID: PMC11866544.

Yu Y, Xie X, Chen Z, Wei J, Ouyang J, Lin Z, Ma J, Guo P, Wu R, Jia L, Gui J. Urine proteomics uncovers biomarker candidates for early identifying rituximab beneficiaries in paediatric steroid-resistant immune thrombocytopenia. Br J Haematol. 2025 Oct;207(4):1323-1333. doi: 10.1111/bjh.70072. Epub 2025 Aug 8. PMID: 40781812.

Zhu G, Yue H, He J, Wang C, Xu C, Jia C, Wang X, Yan Y, Wang B, Zhang H, Chen X, Qiu J, Gao L, Zheng J, Lv G, Yang J, Luo Y, Qin M, Gui J, Mou W. An atypical adolescent case of leukocyte adhesion deficiency I caused by a novel ITGB2 splicing variant with successful immune reconstitution following hematopoietic stem cell transplantation. Clin Exp Immunol. 2025 Jan 21;219(1):uxaf024. doi: 10.1093/cei/uxaf024. PMID: 40531141; PMCID: PMC12203908.

Wang Q, Li S, Wei Y, Xu C, Liu X, Wang X, Chai W, Mou W, Chen X, Li C, Wang C, Gui J. An increase in IL-10-producing DNT cells is associated with the pathogenesis of pediatric SLE. Clin Immunol. 2025 Jul;276:110490. doi: 10.1016/j.clim.2025.110490. Epub 2025 Mar 28. PMID: 40158789.

Fu X, Wang H, Chai W, Chen X, Song D, Wang W, Zhong J, Liu Z, Tong X, Xiong H, Ren X, Gui J. Pathogenic mechanisms and clinical insights into B3GALNT2-related alpha-dystroglycanopathies. J Neuromuscul Dis. 2025 Nov;12(6):814-827. doi: 10.1177/22143602251360270. Epub 2025 Jul 15. PMID: 40665687.

Yu Y, Chen Z, Wei J, Xie X, Ouyang J, Lin Z, Ma J, Guo P, Wu R, Gui J. Urinary metabolomics predicts early rituximab response in steroid-nonresponsive pediatric patients with primary immune thrombocytopenia. Ann Hematol. 2025 Aug;104(8):4057-4070. doi: 10.1007/s00277-025-06453-4. Epub 2025 Jun 20. PMID: 40540043; PMCID: PMC12432038.

Zhao F, Liu X, Gui J, Sun H, Zhang N, Peng Y, Ge M, Wang W. Characterization of immune microenvironment associated with medulloblastoma metastasis based on explainable machine learning. Pediatr Investig. 2025 Feb 14;9(1):59-69. doi: 10.1002/ped4.12471. PMID: 40241883; PMCID: PMC11998180.

Lu Z, Mou W, He J, Ge X, Wang X, Gui J. Spontaneous NETosis and type I IFN signaling activation in resting neutrophils of chronic granulomatous disease patients with CYBB mutations. Genes Dis. 2023 Sep 20;11(6):101118. doi: 10.1016/j.gendis.2023.101118. PMID: 39070548; PMCID: PMC11278796.

Wang G, Liu S, Kong X, Jiao H, Tong F, Guo Z, Zhang M, Guan X, Ren N, Li W, Qi L, Wei Y. Lipocalin-2 induced LDHA expression promotes vascular remodelling in pulmonary hypertension. Cell Prolif. 2024 Dec;57(12):e13717. doi: 10.1111/cpr.13717. Epub 2024 Jul 18. PMID: 39021353; PMCID: PMC11628741.

Lu Z, Wang X, Feng J, Chai W, Wang W, Wang Q, Yang S, Yang W, Su Y, Mou W, Peng Y, Wang H, Gui J. Intratumoral CXCR4hi neutrophils display ferroptotic and immunosuppressive signatures in hepatoblastoma. Front Immunol. 2024 Feb 29;15:1363454. doi: 10.3389/fimmu.2024.1363454. PMID: 38487536; PMCID: PMC10937446.

Peng Y, Wang W, Liu X, Li S, Zhang J, Ni X, Gui J. Characterization of HPV6/11-reactive T-cell subsets in papillomas of patients with juvenile-onset recurrent respiratory papillomatosis and identification of HPV11 E7-specific candidate TCR clonotypes. J Virol. 2024 Oct 22;98(10):e0067724. doi: 10.1128/jvi.00677-24. Epub 2024 Sep 11. PMID: 39258910; PMCID: PMC11495051.

李诗兰,王桂香,王国亮,. 幼年型复发性呼吸道乳头状瘤病中抑制性细胞因子与疾病严重程度的相关性研究[J]. 中国耳鼻咽喉头颈外科,2024,31(6):386-390.

Mou W, Zhao Z, Gao L, Fu L, Li J, Jiao A, Peng Y, Yu T, Guo Y, Chen L, Wang H, Liu J, Qin Q, Xu B, Liu X, He J, Gui J. An Atypical Incontinentia Pigmenti Female with Persistent Mucocutaneous Hyperinflammation and Immunodeficiency Caused by a Novel Germline IKBKG Missense Mutation. J Clin Immunol. 2023 Nov;43(8):2165-2180. doi: 10.1007/s10875-023-01564-x. Epub 2023 Oct 13. PMID: 37831401.

Chai W, Wang X, Lu Z, Zhang S, Wang W, Wang H, Chen C, Yang W, Cheng H, Wang H, Feng J, Yang S, Li Q, Song W, Jin F, Zhang H, Su Y, Gui J. Elevated exosome-transferrable lncRNA EPB41L4A-AS1 in CD56bright NK cells is responsible for the impaired NK function in neuroblastoma patients by suppressing cell glycolysis. Clin Immunol. 2023 May;250:109322. doi: 10.1016/j.clim.2023.109322. Epub 2023 Apr 5. PMID: 37024023.

Liu X, Gui J, Wang X. Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses. Genes Dis. 2023 Mar 27;10(6):2233–6. doi: 10.1016/j.gendis.2023.02.032. Epub ahead of print. PMID: 37362776; PMCID: PMC10041865.

Xiao H, Mou W, Zhang R, Guo X, Chen H, Zhang L, Liu G, Gui J. Manifestations of B-cell expansion with NF-κB and T-cell anergy disease overlapping with hemophagocytic lymphohistiocytosis. Scand J Immunol. 2023 Apr;97(4):e13256. doi: 10.1111/sji.13256. Epub 2023 Feb 9. PMID: 37401643.

Mou W, Yang Z, Wang X, Hei M, Wang Y, Gui J. Immunological assessment of a patient with Omenn syndrome resulting from compound heterozygous mutations in the RAG1 gene. Immunogenetics. 2023 Aug;75(4):385-393. doi: 10.1007/s00251-023-01309-5. Epub 2023 Jun 3. PMID: 37269334.

Gu H, Mou W, Chen Z, Xie X, Yao J, Zhang R, Wu R, Gui J. Case report: Effectiveness of sirolimus in treating partial DiGeorge Syndrome with Autoimmune Lymphoproliferative Syndrome (ALPS)-like features. Front Pediatr. 2023 Jan 18;10:1014249. doi: 10.3389/fped.2022.1014249. PMID: 36741091; PMCID: PMC9889826.

Zou P, Li G, Ge X, Wang J, Wang X, Li Y, Liu Y, Zhang J, Gui J*, Wang Y*. Lymphocyte subset changes in neonates with respiratory syncytial virus pneumonia. J Infect. 2022 May 24:S0163-4453(22)00314-0.

Xi Y, Wang W, Wang H, Wang X, Zhang J, Zhao J, Wang G, Gui J, Ni X. Impaired HPV-specific T-cell response in juvenile-onset recurrent respiratory papillomatosis patients. Clin Immunol. 2022 May 27;241:109046.

Chen X, Liu F, Zheng B, Kang X, Wang X, Mou W, Zhang H, Jiao A, Zhao S, Gui J. Exhausted and Apoptotic BALF T Cells in Proinflammatory Airway Milieu at Acute Phase of Severe Mycoplasma Pneumoniae Pneumonia in Children. Front Immunol. 2022 Jan 17;12:760488.

Li Y, Wang X, Yang H, Li Y, Gui J, Cui Y. Profiles of Proinflammatory Cytokines and T Cells in Patients With Tourette Syndrome: A Meta-Analysis. Front Immunol. 2022 May 26;13:843247.

Wang H, Wang X, Wang W, Chai W, Song W, Zhang H, Mou W, Pei M, Su Y, Ma X, Gui J. Interleukin-15 enhanced the survival of human γδT cells by regulating the expression of Mcl-1 in neuroblastoma. Cell Death Discov. 2022 Mar 29;8(1):139.

Liu X, Pei M, Yu Y, Wang X, Gui J. Reduction of LPAR1 Expression in Neuroblastoma Promotes Tumor Cell Migration. Cancers 2022, 14, 3346.

Wang W, Xi Y, Li S, Liu X, Wang G, Wang H, Pei M, Zhang J, Gui J*, Ni X*. Restricted Recruitment of NK Cells with Impaired Function Is Caused by HPV-Driven Immunosuppressive Microenvironment of Papillomas in Aggressive Juvenile-Onset Recurrent Respiratory Papillomatosis Patients. J Virol. 2022 Sep 26:e0094622. doi: 10.1128/jvi.00946-22.

Pei M, Chai W, Wang X, Duan Y, Wang H, Xi Y, Mou W, Wang W, Chen X, Zhang H, Li Q, Song W, Wang H, Ma X, Gui J. The transcription factor TOX is involved in the regulation of T-cell exhaustion in neuroblastoma. Immunol Lett. 2022 Jun 9;248:16-25.

Chai W, Zhang X, Lin M, Chen Z, Wang X, Wang C, Chen A, Wang C, Wang H, Yue H, Gui J. Allergic rhinitis, allergic contact dermatitis and disease comorbidity belong to separate entities with distinct composition of T-cell subsets, cytokines, immunoglobulins and autoantibodies. Allergy Asthma Clin Immunol. 2022 Feb 11;18(1):10.


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